Pharmaceutical intermediates |
Name |
Key intermediate |
CAS NO |
Axitinib | 3,6-diiodo(1H)indazole Methyl 2-mercaptobenzoate |
319472-78-1 4892-02-8 |
Crizotinib | 4-Iodo-1H-pyrazole (R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-2-nitropyridine 4-(4-Bromopyrazol-1-yl)piperidine-1-carboxylic acid tert-butyl ester (R)-5-bromo-3-(1- |
3469-69-0 877397-70-1 877399-50-3 877399-00-3 |
Lapatinib | 2-(Methylsulfonyl)-ethanamine hydrochloride N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine 3-Chloro-4-(3-fluorobenzyloxy)aniline |
104458-24-4 231278-20-9 202197-26-0 |
Pazopanib | 3-Methyl-6-nitro-1H-Indazole 2,3-dimethyl-6-nitro-2H-indazole 2,3-dimethyl-2H-indazol-6-amine 2,4-Dichloropyrimidine 3-Amino-6-methylbenzenesulfonam |
6494-19-5 444731-73-1 444731-72-0 3934-20-1 6973-09-7 |
Regorafenib | 3-Fluoro-4-Nitrophenol 3-Fluoro-4-aminophenol |
394-41-2 399-95-1 |
Afatinib | trans 4-Dimethylaminocrotonic acid hydrochloride |
848133-35-7 |